Imitrex: Uses, Dosage, Side Effects & Warnings

Foods containing soy and cottonseed meal can make Synthroid less effective. Walnuts, grapefruit juice, and dietary fiber can also make Synthroid less effective. If you eat any of these on a regular basis, check with your doctor. If you suspect hypothyroidism, consult a physician for a professional assessment. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Imitrex only for the indication prescribed. Enter medications to view a detailed interaction report using our Drug Interaction Checker.

9 Drug-Food Interactions

SYNTHROID® (levothyroxine sodium) tablets, for oral use is a prescription, man-made thyroid hormone that is used to treat a condition called hypothyroidism in adults and children, including infants. It is meant to replace a hormone that is usually made by your thyroid gland. Generally, thyroid replacement treatment is to be taken for life.

Related/similar drugs

SYNTHROID is not indicated for suppression of benign thyroid nodules and nontoxic diffuse goiter in iodine-sufficient patients, as there are no clinical benefits and overtreatment with SYNTHROID may induce hyperthyroidism. This is a key issue for some of the elemental things like calcium and iron, that can interfere with thyroid hormone absorption and thus should be taken approximately 4 hours apart. Particularly when SYNTHROID is written in a non-protective manner for the state language.

Always pay attention to the laboratory working on your result, as the normal ranges may vary. Ubrelvy (ubrogepant) tablets are used for the acute treatment of migraine. This is not a complete list of side effects and others may occur. Overdose symptoms may include tremors, skin redness in your arms or legs, weakness, loss of coordination, breathing problems, blue-colored lips or fingernails, vision problems, or a seizure (convulsions). Since Imitrex is used when needed, it does not have a daily dosing schedule. Call your doctor if your symptoms do not improve after using this medicine.

The physiological actions of thyroid hormones are produced predominantly by T3, the majority of which (approximately 80%) is derived from T4 by deiodination in peripheral tissues. Biotin supplementation is known tointerfere with thyroid hormone immunoassays that are based on a biotin and streptavidin interaction, which may result in erroneous thyroid hormone test results. Stop biotin and biotin-containing supplements for at least 2 days prior to thyroid testing. Consumption of certain foods may affect SYNTHROID absorption thereby necessitating adjustments in dosing see Dosage and Administration (2.1). Soybean flour, cottonseed meal, walnuts, and dietary fiber may bind and decrease the absorption of SYNTHROID from the gastrointestinal tract. Grapefruit juice may delay the absorption of levothyroxine and reduce its bioavailability.

• Luckily, even though underactive thyroid is such a multidirectional disease, hypothyroidism treatment is easy, cheap, and obvious — you have to replace the lacking endogenous hormones with synthetic ones.
• In addition, many drugs and foods affect T4 absorption see Drug Interactions (7).
• HypothyroidismSYNTHROID® (levothyroxine sodium) tablets, for oral use is indicated as a replacement therapy in primary (thyroidal), secondary (pituitary), and tertiary (hypothalamic) congenital or acquired hypothyroidism.
• Many drugs and physiologic conditions affect the binding of thyroid hormones to serum proteins see Drug Interactions (7).
• Assess compliance, dose of medication administered, and method of administration prior to increasing the dose of SYNTHROID see Warnings and Precautions (5.1) and Use in Specific Populations (8.4).

The higher affinity of both TBG and TBPA for T4 partially explains the higher serum levels, slower metabolic clearance, and longer half-life of T4 compared to T3. Protein-bound thyroid hormones exist in reverse equilibrium with small amounts of free hormone. Many drugs and physiologic conditions affect the binding of thyroid hormones to serum proteins see Drug Interactions (7). Thyroid hormones do not readily cross the placental barrier see Use in Specific Populations (8.1).

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Levothyroxine is one of the ten NTI drug classes most commonly prescribed. These medications are those synthroid news where small changes in the dose or blood concentration may lead to serious therapeutic failures and/or adverse drug reactions. Using multivitamin with minerals together with levothyroxine may decrease the effects of levothyroxine. You should separate the administration of levothyroxine and multivitamin with minerals by at least 4 hours. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. Oral levothyroxine sodium is a synthetic T4 hormone that exerts the same physiologic effect as endogenous T4, thereby maintaining normal T4 levels when a deficiency is present.

TO INDICATE A PRESCRIPTION IS DAW-1

Usually it should be taken at least 30 to 60 minutes before eating breakfast, or at bedtime (3 or more hours after the evening meal). Taking it on an empty stomach results in the best absorption of the drug from the intestine. Add your drug list to My Med List to view medical information in a simple, easy-to-read, personalized format. Automatically receive FDA alerts, drug interaction warnings, plus data on food, allergy & condition interactions. Consider changes in TBG concentration when interpreting T4 and T3 values.

You should take your medication every day on an empty stomach, preferably 0.5h-1h before breakfast (alternatively, you can take the dose at bedtime, at least 3 hours after the last meal). You should avoid taking iron or calcium supplements within four hours of levothyroxine dose – they decrease hormone absorption. Personally, I have had experiences where I have written for brand-name SYNTHROID and the patients have been dispensed generic levothyroxine or even another branded levothyroxine product. It’s very important to make sure that you write “Dispense as written,” or whatever state-specific language, on the prescription when you prescribe the medication. And to adjust the dose based on periodic assessment of the patient’s clinical response and their laboratory values.